FGF-2 Polyclonal Antibody
¥680.00
APLP2 (phospho Tyr755) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2611856
- 产品信息
商品描述
靶点-Target
APLP2
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
87kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human APLP2 around the phosphorylation site of Tyr755. AA range:714-763
特异性
Phospho-APLP2 (Y755) Polyclonal Antibody detects endogenous levels of APLP2 protein only when phosphorylated at Y755.
基因名称
APLP2
蛋白名称
Amyloid-like protein 2
别名
APLP2;APPL2;Amyloid-like protein 2;APLP-2;APPH;Amyloid protein homolog;CDEI box-binding protein;CDEBP
Organism-1
Human
基因ID-1
334
SwissProt-1
Q06481
Organism-2
Mouse
基因ID-2
11804
SwissProt-2
Q06335
Organism-3
Rat
SwissProt-3
P15943
背景
This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Nucleus .
