FGF-2 Polyclonal Antibody
¥680.00
TTK (phospho Thr676) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2611839
- 产品信息
商品描述
靶点-Target
TTK
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
97kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TTK around the phosphorylation site of Thr676. AA range:642-691
特异性
Phospho-TTK (T676) Polyclonal Antibody detects endogenous levels of TTK protein only when phosphorylated at T676.
基因名称
TTK
蛋白名称
Dual specificity protein kinase TTK
别名
TTK;MPS1;MPS1L1;Dual specificity protein kinase TTK;Phosphotyrosine picked threonine-protein kinase;PYT
Organism-1
Human
基因ID-1
7272
SwissProt-1
P33981
Organism-2
Mouse
SwissProt-2
P35761
背景
TTK protein kinase(TTK) Homo sapiens This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009],
细胞定位
kinetochore,cytoplasm,spindle,membrane,
