FGF-2 Polyclonal Antibody
¥680.00
Blk (phospho Tyr501) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
一键复制产品信息
产品规格：
- 50μL
- 100μL
货号：
FAB2611815
- 产品信息
商品描述
靶点-Target
BLK
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
58kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human BLK around the phosphorylation site of Tyr501. AA range:456-505
特异性
Phospho-Blk (Y501) Polyclonal Antibody detects endogenous levels of Blk protein only when phosphorylated at Y501.
基因名称
BLK
蛋白名称
Tyrosine-protein kinase Blk
别名
BLK;Tyrosine-protein kinase Blk;B lymphocyte kinase;p55-Blk
Organism-1
Human
基因ID-1
640
SwissProt-1
P51451
Organism-2
Mouse
基因ID-2
12143
SwissProt-2
P16277
背景
This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010],
细胞定位
Cell membrane ; Lipid-anchor . Present and active in lipid rafts. Membrane location is required for the phosphorylation of CD79A and CD79B (By similarity). .
