FGF-2 Polyclonal Antibody
¥680.00
IGF-IR (phospho Tyr1346) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2611804
- 产品信息
商品描述
靶点-Target
IGF-1R
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
155kD
MW(Observed)
pro:155kD,recetor beta:95kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human IGF1R around the phosphorylation site of Tyr1346. AA range:1311-1360
特异性
Phospho-IGF-IR (Y1346) Polyclonal Antibody detects endogenous levels of IGF-IR protein only when phosphorylated at Y1346.
基因名称
IGF1R
蛋白名称
Insulin-like growth factor 1 receptor
别名
IGF1R;Insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;IGF-I receptor;CD antigen CD221
Organism-1
Human
基因ID-1
3480
SwissProt-1
P08069
Organism-2
Mouse
基因ID-2
16001
SwissProt-2
Q60751
Organism-3
Rat
基因ID-3
25718
SwissProt-3
P24062
背景
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],
细胞定位
Cell membrane ; Single-pass type I membrane protein .
