Max (phospho Ser2) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611787
- 产品信息
商品描述
靶点-Target
Max
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
18kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MAX around the phosphorylation site of Ser2. AA range:1-50
特异性
Phospho-Max (S2) Polyclonal Antibody detects endogenous levels of Max protein only when phosphorylated at S2.
基因名称
MAX
蛋白名称
Protein max
别名
MAX;BHLHD4;Protein max;Class D basic helix-loop-helix protein 4;bHLHd4;Myc-associated factor X
Organism-1
Human
基因ID-1
4149
SwissProt-1
P61244
Organism-2
Mouse
SwissProt-2
P28574
Organism-3
Rat
基因ID-3
60661
SwissProt-3
P52164
背景
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],
细胞定位
Nucleus. Cell projection, dendrite .





