Max (phospho Ser2) Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611787

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商品描述
  • 靶点-Target

    Max

  • 反应性

    Human,Mouse,Rat

  • 应用

    IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Calculated)

    18kD

  • 推荐稀释比

    IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human MAX around the phosphorylation site of Ser2. AA range:1-50

  • 特异性

    Phospho-Max (S2) Polyclonal Antibody detects endogenous levels of Max protein only when phosphorylated at S2.

  • 基因名称

    MAX

  • 蛋白名称

    Protein max

  • 别名

    MAX;BHLHD4;Protein max;Class D basic helix-loop-helix protein 4;bHLHd4;Myc-associated factor X

  • Organism-1

    Human

  • 基因ID-1

    4149

  • SwissProt-1

    P61244

  • Organism-2

    Mouse

  • SwissProt-2

    P28574

  • Organism-3

    Rat

  • 基因ID-3

    60661

  • SwissProt-3

    P52164

  • 背景

    The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],

  • 细胞定位

    Nucleus. Cell projection, dendrite .