FGF-2 Polyclonal Antibody
¥680.00
MARK1/2/3/4 (phospho Thr215) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2611786
- 产品信息
商品描述
靶点-Target
MARK1/2/3/4
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
89kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MARK1/2/3/4 around the phosphorylation site of Thr215. AA range:181-230
特异性
Phospho-MARK1/2/3/4 (T215) Polyclonal Antibody detects endogenous levels of MARK1/2/3/4 protein only when phosphorylated at T215.
基因名称
MARK1/2/3/4
蛋白名称
Serine/threonine-protein kinase MARK1/2/3/4
别名
MARK1;KIAA1477;MARK;Serine/threonine-protein kinase MARK1;MAP/microtubule affinity-regulating kinase 1;PAR1 homolog c;Par-1c;Par1c;MARK2;EMK1;Serine/threonine-protein kinase MARK2;ELKL motif kinase 1;EMK-1;MAP/microtubule affin
Organism-1
Human
基因ID-1
4139;2011;4140;57787
SwissProt-1
Q9P0L2;Q7KZI7;P27448;Q96L34
Organism-2
Mouse
基因ID-2
226778;13728;17169;232944
Organism-3
Rat
基因ID-3
117016;60328;170577
SwissProt-3
O08678;O08679;Q8VHF0
背景
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-215 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:May play a role in cytoskeletal stability.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily.,similarity:Contains 1 KA1 (kinase-associated) domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UBA domain.,subcellular location:Appears to localize to an intracellular network.,tissue specificity:Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.,
细胞定位
Cell membrane ; Peripheral membrane protein . Cytoplasm, cytoskeleton . Cytoplasm . Cell projection, dendrite . Appears to localize to an intracellular network. .
