Tuberin (phospho Thr1462) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611747
- 产品信息
商品描述
靶点-Target
Tuberin
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
200kD
推荐稀释比
WB 1:500-2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Tuberin/TSC2 around the phosphorylation site of Thr1462. AA range:1428-1477
特异性
Phospho-Tuberin (T1462) Polyclonal Antibody detects endogenous levels of Tuberin protein only when phosphorylated at T1462.
基因名称
TSC2
蛋白名称
Tuberin
别名
TSC2;TSC4;Tuberin;Tuberous sclerosis 2 protein
Organism-1
Human
基因ID-1
7249
SwissProt-1
P49815
Organism-2
Mouse
SwissProt-2
Q61037
Organism-3
Rat
基因ID-3
24855
SwissProt-3
P49816
背景
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes.





