Rhodopsin (phospho Ser334) Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611745

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商品描述
  • 靶点-Target

    Rhodopsin

  • 反应性

    Human,Mouse,Rat

  • 应用

    IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Calculated)

    39kD

  • 推荐稀释比

    IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human Rhodopsin around the phosphorylation site of Ser334. AA range:299-348

  • 特异性

    Phospho-Rhodopsin (S334) Polyclonal Antibody detects endogenous levels of Rhodopsin protein only when phosphorylated at S334.

  • 基因名称

    RHO

  • 蛋白名称

    Rhodopsin

  • 别名

    RHO;OPN2;Rhodopsin;Opsin-2

  • Organism-1

    Human

  • 基因ID-1

    6010

  • SwissProt-1

    P08100

  • Organism-2

    Mouse

  • 基因ID-2

    212541

  • SwissProt-2

    P15409

  • Organism-3

    Rat

  • 基因ID-3

    24717

  • SwissProt-3

    P51489

  • 背景

    Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Membrane ; Multi-pass membrane protein . Cell projection, cilium, photoreceptor outer segment . Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia. .