SSB (phospho Ser366) Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611724

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商品描述
  • 靶点-Target

    SSB

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    47kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human SSB around the phosphorylation site of Ser366. AA range:341-390

  • 特异性

    Phospho-SSB (S366) Polyclonal Antibody detects endogenous levels of SSB protein only when phosphorylated at S366.

  • 基因名称

    SSB

  • 蛋白名称

    Lupus La protein

  • 别名

    SSB;Lupus La protein;La autoantigen;La ribonucleoprotein;Sjoegren syndrome type B antigen;SS-B

  • Organism-1

    Human

  • 基因ID-1

    6741

  • SwissProt-1

    P05455

  • Organism-2

    Mouse

  • SwissProt-2

    P32067

  • 背景

    Sjogren syndrome antigen B(SSB) Homo sapiens The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein. [provided by RefSeq, Jun 2014],

  • 细胞定位

    Nucleus .