ENaC β (phospho Thr615) Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611720

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商品描述
  • 靶点-Target

    ENaC β

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    68kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human Nonvoltage-gated Sodium Channel 1 around the phosphorylation site of Thr615. AA range:581-630

  • 特异性

    Phospho-ENaC β (T615) Polyclonal Antibody detects endogenous levels of ENaC β protein only when phosphorylated at T615.

  • 基因名称

    SCNN1B

  • 蛋白名称

    Amiloride-sensitive sodium channel subunit beta

  • 别名

    SCNN1B;Amiloride-sensitive sodium channel subunit beta;Beta-NaCH;Epithelial Na;+;channel subunit beta;Beta-ENaC;ENaCB;Nonvoltage-gated sodium channel 1 subunit beta;SCNEB

  • Organism-1

    Human

  • 基因ID-1

    6338

  • SwissProt-1

    P51168

  • Organism-2

    Mouse

  • 基因ID-2

    20277

  • SwissProt-2

    Q9WU38

  • Organism-3

    Rat

  • 基因ID-3

    24767

  • SwissProt-3

    P37090

  • 背景

    Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome. [provided by RefSeq, Apr 2009],

  • 细胞定位

    Apical cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane . Apical membrane of epithelial cells. .