FGF-2 Polyclonal Antibody
¥680.00
Kv1.3 (phospho Tyr187) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
一键复制产品信息
产品规格：
- 50μL
- 100μL
货号：
FAB2611718
- 产品信息
商品描述
靶点-Target
Kv1.3
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
58kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Kv1.3/KCNA3 around the phosphorylation site of Tyr135. AA range:101-150
特异性
Phospho-Kv1.3 (Y187) Polyclonal Antibody detects endogenous levels of Kv1.3 protein only when phosphorylated at Y187.
基因名称
KCNA3
蛋白名称
Potassium voltage-gated channel subfamily A member 3
别名
KCNA3;HGK5;Potassium voltage-gated channel subfamily A member 3;HGK5;HLK3;HPCN3;Voltage-gated K;+;channel HuKIII;Voltage-gated potassium channel subunit Kv1.3
Organism-1
Human
基因ID-1
3738
SwissProt-1
P22001
Organism-2
Mouse
基因ID-2
16491
SwissProt-2
P16390
Organism-3
Rat
基因ID-3
29731
SwissProt-3
P15384
背景
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and
细胞定位
Cell membrane ; Multi-pass membrane protein.
