Hrs (phospho Tyr334) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611714
- 产品信息
商品描述
靶点-Target
Hrs
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
86kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human HRS around the phosphorylation site of Tyr334. AA range:301-350
特异性
Phospho-Hrs (Y334) Polyclonal Antibody detects endogenous levels of Hrs protein only when phosphorylated at Y334.
基因名称
HGS
蛋白名称
Hepatocyte growth factor-regulated tyrosine kinase substrate
别名
HGS;HRS;Hepatocyte growth factor-regulated tyrosine kinase substrate;Hrs;Protein pp110
Organism-1
Human
基因ID-1
9146
SwissProt-1
O14964
Organism-2
Mouse
基因ID-2
15239
SwissProt-2
Q99LI8
Organism-3
Rat
基因ID-3
56084
SwissProt-3
Q9JJ50
背景
The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010],
细胞定位
Cytoplasm . Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Endosome, multivesicular body membrane ; Peripheral membrane protein . Colocalizes with UBQLN1 in ubiquitin-rich cytoplasmic aggregates that are not endocytic compartments. .





