IFN-γRα (phospho Tyr457) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611705
- 产品信息
商品描述
靶点-Target
IFN-γRα
反应性
Human,Mouse,Rat,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
83kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Interferon-gamma Receptor alpha around the phosphorylation site of Tyr457. AA range:431-480
特异性
Phospho-IFN-γRα (Y457) Polyclonal Antibody detects endogenous levels of IFN-γRα protein only when phosphorylated at Y457.
基因名称
IFNGR1
蛋白名称
Interferon gamma receptor 1
别名
IFNGR1;Interferon gamma receptor 1;IFN-gamma receptor 1;IFN-gamma-R1;CDw119;CD antigen CD119
Organism-1
Human
基因ID-1
3459
SwissProt-1
P15260
Organism-2
Mouse
基因ID-2
15979
SwissProt-2
P15261
背景
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Single-pass type I membrane protein .





