p120 (phospho Tyr228) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611698
- 产品信息
商品描述
靶点-Target
p120 Catenin
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
108kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Catenin-delta1 around the phosphorylation site of Tyr228. AA range:201-250
特异性
Phospho-p120 (Y228) Polyclonal Antibody detects endogenous levels of p120 protein only when phosphorylated at Y228.
基因名称
CTNND1
蛋白名称
Catenin delta-1
别名
CTNND1;KIAA0384;Catenin delta-1;Cadherin-associated Src substrate;CAS;p120 catenin;p120;ctn;p120;cas;
Organism-1
Human
基因ID-1
1500
SwissProt-1
O60716
Organism-2
Mouse
基因ID-2
12388
SwissProt-2
P30999
背景
catenin delta 1(CTNND1) Homo sapiens This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. [provided by RefSeq, Dec 2010],
细胞定位
Cell junction, adherens junction . Cytoplasm . Nucleus . Cell membrane . Interaction with GLIS2 promotes nuclear translocation (By similarity). Detected at cell-cell contacts (PubMed:15240885, PubMed:17047063). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm (PubMed:17047063). CDH1 enhances cell membrane localization (PubMed:15240885). Isoforms 4A and 1AB are excluded from the nucleus (PubMed:11896187). .; [Isoform 1A]: Nucleus .; [Isoform 2A]: Nucleus .; [Isoform 3A]: Nucleus .





