FGF-2 Polyclonal Antibody
¥680.00
Vav3 (phospho Tyr173) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
一键复制产品信息
产品规格：
- 50μL
- 100μL
货号：
FAB2611619
- 产品信息
商品描述
靶点-Target
Vav3
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
100kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phospho-peptide around the phosphorylation site of human Vav3 (phospho Tyr173)
特异性
Phospho-Vav3 (Y173) Polyclonal Antibody detects endogenous levels of Vav3 protein only when phosphorylated at Y173.
基因名称
VAV3
蛋白名称
Guanine nucleotide exchange factor VAV3
别名
VAV3;Guanine nucleotide exchange factor VAV3;VAV-3
Organism-1
Human
基因ID-1
10451
SwissProt-1
Q9UKW4
Organism-2
Mouse
基因ID-2
57257
SwissProt-2
Q9R0C8
背景
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
细胞定位
intracellular,cytosol,plasma membrane,extracellular exosome,
