Gab 2 (phospho Ser623) Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611598

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商品描述
  • 靶点-Target

    Gab2

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    80kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human Gab2 around the phosphorylation site of Ser623. AA range:589-638

  • 特异性

    Phospho-Gab 2 (S623) Polyclonal Antibody detects endogenous levels of Gab 2 protein only when phosphorylated at S623.

  • 基因名称

    GAB2

  • 蛋白名称

    GRB2-associated-binding protein 2

  • 别名

    GAB2;KIAA0571;GRB2-associated-binding protein 2;GRB2-associated binder 2;Growth factor receptor bound protein 2-associated protein 2;pp100

  • Organism-1

    Human

  • 基因ID-1

    9846

  • SwissProt-1

    Q9UQC2

  • Organism-2

    Mouse

  • SwissProt-2

    Q9Z1S8

  • Organism-3

    Rat

  • 基因ID-3

    84477

  • SwissProt-3

    Q9EQH1

  • 背景

    GRB2 associated binding protein 2(GAB2) Homo sapiens This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009],

  • 细胞定位

    Cytoplasm . Cell membrane .