FGF-2 Polyclonal Antibody
¥680.00
Trk C (phospho Tyr516) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2611580
- 产品信息
商品描述
靶点-Target
Trk C
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
160kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Trk C around the phosphorylation site of Tyr516. AA range:482-531
特异性
Phospho-Trk C (Y516) Polyclonal Antibody detects endogenous levels of Trk C protein only when phosphorylated at Y516.
基因名称
NTRK3
蛋白名称
NT-3 growth factor receptor
别名
NTRK3;TRKC;NT-3 growth factor receptor;GP145-TrkC;Trk-C;Neurotrophic tyrosine kinase receptor type 3;TrkC tyrosine kinase
Organism-1
Human
基因ID-1
4916
SwissProt-1
Q16288
Organism-2
Mouse
基因ID-2
18213
SwissProt-2
Q6VNS1
Organism-3
Rat
基因ID-3
29613
SwissProt-3
Q03351
背景
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011],
细胞定位
Membrane; Single-pass type I membrane protein.
