SPAK (phospho Ser309) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611579
- 产品信息
商品描述
靶点-Target
SPAK
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
60kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human STK39 around the phosphorylation site of Ser311. AA range:277-326
特异性
Phospho-SPAK (S311) Polyclonal Antibody detects endogenous levels of SPAK protein only when phosphorylated at S311.
基因名称
STK39
蛋白名称
STE20/SPS1-related proline-alanine-rich protein kinase
别名
STK39;SPAK;STE20/SPS1-related proline-alanine-rich protein kinase;Ste-20-related kinase;DCHT;Serine/threonine-protein kinase 39
Organism-1
Human
基因ID-1
27347
SwissProt-1
Q9UEW8
Organism-2
Mouse
基因ID-2
53416
SwissProt-2
Q9Z1W9
Organism-3
Rat
基因ID-3
54348
SwissProt-3
O88506
背景
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Nucleus when caspase-cleaved. .





