PAKβ (phospho Ser154) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611575
- 产品信息
商品描述
靶点-Target
PAKβ
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
72kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PAK3 around the phosphorylation site of Ser154. AA range:121-170
特异性
Phospho-PAKβ (S154) Polyclonal Antibody detects endogenous levels of PAKβ protein only when phosphorylated at S154.
基因名称
PAK3
蛋白名称
Serine/threonine-protein kinase PAK 3
别名
PAK3;OPHN3;Serine/threonine-protein kinase PAK 3;Beta-PAK;Oligophrenin-3;p21-activated kinase 3;PAK-3
Organism-1
Human
基因ID-1
5063
SwissProt-1
O75914
Organism-2
Mouse
基因ID-2
18481
SwissProt-2
Q61036
Organism-3
Rat
基因ID-3
29433
SwissProt-3
Q62829
背景
The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Apr 2016],
细胞定位
Cytoplasm .





