MEK Kinase-1 (phospho Thr1402) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611566
- 产品信息
商品描述
靶点-Target
MEK Kinase-1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
160kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MAP3K1 around the phosphorylation site of Thr1402. AA range:1368-1417
特异性
Phospho-MEK Kinase-1 (T1402) Polyclonal Antibody detects endogenous levels of MEK Kinase-1 protein only when phosphorylated at T1402.
基因名称
MAP3K1
蛋白名称
Mitogen-activated protein kinase kinase kinase 1
别名
MAP3K1;MAPKKK1;MEKK;MEKK1;Mitogen-activated protein kinase kinase kinase 1;MAPK/ERK kinase kinase 1;MEK kinase 1;MEKK 1
Organism-1
Human
基因ID-1
4214
SwissProt-1
Q13233
Organism-2
Mouse
SwissProt-2
P53349
Organism-3
Rat
基因ID-3
116667
SwissProt-3
Q62925
背景
The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012],
细胞定位
cytoplasm,cytosol,





