Vimentin (phospho Ser56) Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611547

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商品描述
  • 靶点-Target

    Vimentin

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    54kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human Vimentin around the phosphorylation site of Ser56. AA range:31-80

  • 特异性

    Phospho-Vimentin (S56) Polyclonal Antibody detects endogenous levels of Vimentin protein only when phosphorylated at S56.

  • 基因名称

    VIM

  • 蛋白名称

    Vimentin

  • 别名

    VIM;Vimentin

  • Organism-1

    Human

  • 基因ID-1

    7431

  • SwissProt-1

    P08670

  • Organism-2

    Mouse

  • SwissProt-2

    P20152

  • 背景

    This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009],

  • 细胞定位

    Cytoplasm . Cytoplasm, cytoskeleton . Nucleus matrix . Cell membrane .