JAK3 (phospho Tyr785) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611536
- 产品信息
商品描述
靶点-Target
JAK3
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
125kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human JAK3 around the phosphorylation site of Tyr785. AA range:751-800
特异性
Phospho-JAK3 (Y785) Polyclonal Antibody detects endogenous levels of JAK3 protein only when phosphorylated at Y785.
基因名称
JAK3
蛋白名称
Tyrosine-protein kinase JAK3
别名
JAK3;Tyrosine-protein kinase JAK3;Janus kinase 3;JAK-3;Leukocyte janus kinase;L-JAK
Organism-1
Human
基因ID-1
3718
SwissProt-1
P52333
Organism-2
Mouse
基因ID-2
16453
SwissProt-2
Q62137
Organism-3
Rat
SwissProt-3
Q63272
背景
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],
细胞定位
Endomembrane system ; Peripheral membrane protein . Cytoplasm .





