hnRNP C1/2 (phospho Ser260) Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611530

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商品描述
  • 靶点-Target

    hnRNP C1/C2

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    41kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human hnRNP C1/2 around the phosphorylation site of Ser260. AA range:231-280

  • 特异性

    Phospho-hnRNP C1/2 (S260) Polyclonal Antibody detects endogenous levels of hnRNP C1/2 protein only when phosphorylated at S260.

  • 基因名称

    HNRNPC

  • 蛋白名称

    Heterogeneous nuclear ribonucleoproteins C1/C2

  • 别名

    HNRNPC;HNRPC;Heterogeneous nuclear ribonucleoproteins C1/C2;hnRNP C1/C2

  • Organism-1

    Human

  • 基因ID-1

    3183

  • SwissProt-1

    P07910

  • Organism-2

    Mouse

  • 基因ID-2

    15381

  • SwissProt-2

    Q9Z204

  • Organism-3

    Rat

  • SwissProt-3

    P17132

  • 背景

    This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Nucleus. Component of ribonucleosomes.