14-3-3 ζ/δ (phospho Thr232) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611489
- 产品信息
商品描述
靶点-Target
14-3-3 ζ/δ
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
28kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human 14-3-3 zeta/delta around the phosphorylation site of Thr232. AA range:196-245
特异性
Phospho-14-3-3 ζ/δ (T232) Polyclonal Antibody detects endogenous levels of 14-3-3 ζ/δ protein only when phosphorylated at T232.
基因名称
YWHAZ
蛋白名称
14-3-3 protein zeta/delta
别名
YWHAZ;14-3-3 protein zeta/delta;Protein kinase C inhibitor protein 1;KCIP-1
Organism-1
Human
基因ID-1
7534
SwissProt-1
P63104
Organism-2
Mouse
基因ID-2
22631
SwissProt-2
P63101
Organism-3
Rat
基因ID-3
25578
SwissProt-3
P63102
背景
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008],
细胞定位
Cytoplasm . Melanosome . Located to stage I to stage IV melanosomes.





