FGF-2 Polyclonal Antibody
¥680.00
c-Fms (phospho Tyr723) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2611473
- 产品信息
商品描述
靶点-Target
c-Fms
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
130-170kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human M-CSF Receptor around the phosphorylation site of Tyr723. AA range:691-740
特异性
Phospho-c-Fms (Y723) Polyclonal Antibody detects endogenous levels of c-Fms protein only when phosphorylated at Y723.
基因名称
CSF1R
蛋白名称
Macrophage colony-stimulating factor 1 receptor
别名
CSF1R;FMS;Macrophage colony-stimulating factor 1 receptor;CSF-1 receptor;CSF-1-R;CSF-1R;M-CSF-R;Proto-oncogene c-Fms;CD antigen CD115
Organism-1
Human
基因ID-1
1436
SwissProt-1
P07333
Organism-2
Mouse
基因ID-2
12978
SwissProt-2
P09581
Organism-3
Rat
SwissProt-3
Q00495
背景
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],
细胞定位
Cell membrane; Single-pass type I membrane protein.
