Synapsin I (phospho Ser62) Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611452

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商品描述
  • 靶点-Target

    Synapsin I

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    80kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human Synapsin1 around the phosphorylation site of Ser62. AA range:26-75

  • 特异性

    Phospho-Synapsin I (S62) Polyclonal Antibody detects endogenous levels of Synapsin I protein only when phosphorylated at S62.

  • 基因名称

    SYN1

  • 蛋白名称

    Synapsin-1

  • 别名

    SYN1;Synapsin-1;Brain protein 4.1;Synapsin I

  • Organism-1

    Human

  • 基因ID-1

    6853

  • SwissProt-1

    P17600

  • Organism-2

    Mouse

  • 基因ID-2

    20964

  • SwissProt-2

    O88935

  • Organism-3

    Rat

  • 基因ID-3

    24949

  • SwissProt-3

    P09951

  • 背景

    This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cell junction, synapse. Golgi apparatus .