FGF-2 Polyclonal Antibody
¥680.00
PDE4B/C/D (phospho Ser133/119/190) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2611448
- 产品信息
商品描述
靶点-Target
PDE4B/C/D
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
76kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PDE4D around the phosphorylation site of Ser190/53. AA range:156-205
特异性
Phospho-PDE4B/C/D (S133/119/190) Polyclonal Antibody detects endogenous levels of PDE4B/C/D protein only when phosphorylated at S133/119/190.
基因名称
PDE4B/PDE4C/PDE4D
蛋白名称
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
别名
PDE4B;DPDE4;cAMP-specific 3';5'-cyclic phosphodiesterase 4B;DPDE4;PDE32;PDE4C;DPDE1;cAMP-specific 3',5'-cyclic phosphodiesterase 4C;DPDE1;PDE21;PDE4D;DPDE3;cAMP-specific 3',5'-cyclic phosphodiesterase 4D;DPDE3;PDE43
Organism-1
Human
基因ID-1
5144
SwissProt-1
Q07343;Q08493;Q08499
Organism-2
Mouse
基因ID-2
110385;238871
Organism-3
Rat
基因ID-3
24626;24627
SwissProt-3
P14646;P14644;P14270
背景
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],
细胞定位
[Isoform PDE4B5]: Cytoplasm . Cell membrane .
