Artemis (phospho Ser516) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611423
- 产品信息
商品描述
靶点-Target
Artemis
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
78kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Artemis around the phosphorylation site of Ser516. AA range:482-531
特异性
Phospho-Artemis (S516) Polyclonal Antibody detects endogenous levels of Artemis protein only when phosphorylated at S516.
基因名称
DCLRE1C
蛋白名称
Protein artemis
别名
DCLRE1C;ARTEMIS;ASCID;SCIDA;SNM1C;Protein artemis;DNA cross-link repair 1C protein;Protein A-SCID;SNM1 homolog C;hSNM1C;SNM1-like protein
Organism-1
Human
基因ID-1
64421
SwissProt-1
Q96SD1
Organism-2
Mouse
基因ID-2
227525
SwissProt-2
Q8K4J0
背景
This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
细胞定位
Nucleus .





