FGF-2 Polyclonal Antibody
¥680.00
Stat2 (phospho Tyr690) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2611392
- 产品信息
商品描述
靶点-Target
Stat2
反应性
Human,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
113kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human STAT2 around the phosphorylation site of Tyr690. AA range:656-705
特异性
Phospho-Stat2 (Y690) Polyclonal Antibody detects endogenous levels of Stat2 protein only when phosphorylated at Y690.
基因名称
STAT2
蛋白名称
Signal transducer and activator of transcription 2
别名
STAT2;Signal transducer and activator of transcription 2;p113
Organism-1
Human
基因ID-1
6773
SwissProt-1
P52630
Organism-2
Mouse
SwissProt-2
Q9WVL2
背景
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
细胞定位
Cytoplasm . Nucleus . Translocated into the nucleus upon activation by IFN-alpha/beta. .
