FGF-2 Polyclonal Antibody
¥680.00
PLC γ2 (phospho Tyr753) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2611388
- 产品信息
商品描述
靶点-Target
PLCG2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
148kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PLCG2 around the phosphorylation site of Tyr753. AA range:721-770
特异性
Phospho-PLC γ2 (Y753) Polyclonal Antibody detects endogenous levels of PLC γ2 protein only when phosphorylated at Y753.
基因名称
PLCG2
蛋白名称
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
别名
PLCG2;1-phosphatidylinositol 4;5-bisphosphate phosphodiesterase gamma-2;Phosphoinositide phospholipase C-gamma-2;Phospholipase C-IV;PLC-IV;Phospholipase C-gamma-2;PLC-gamma-2
Organism-1
Human
基因ID-1
5336
SwissProt-1
P16885
Organism-2
Mouse
基因ID-2
234779
SwissProt-2
Q8CIH5
Organism-3
Rat
基因ID-3
29337
SwissProt-3
P24135
背景
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014],
细胞定位
intracellular,cytosol,plasma membrane,extracellular exosome,
