eEF2K (phospho Ser366) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611379
- 产品信息
商品描述
靶点-Target
eEF2K
反应性
Human,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
105kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human eEF2K around the phosphorylation site of Ser366. AA range:331-380
特异性
Phospho-eEF2K (S366) Polyclonal Antibody detects endogenous levels of eEF2K protein only when phosphorylated at S366.
基因名称
EEF2K
蛋白名称
Eukaryotic elongation factor 2 kinase
别名
EEF2K;Eukaryotic elongation factor 2 kinase;eEF-2 kinase;eEF-2K;Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
Organism-1
Human
基因ID-1
29904
SwissProt-1
O00418
Organism-2
Mouse
SwissProt-2
O08796
Organism-3
Rat
基因ID-3
25435
SwissProt-3
P70531
背景
This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008],
细胞定位
cytoplasm,cytosol,postsynaptic density,





