FGF-2 Polyclonal Antibody
¥680.00
TH (phospho Ser62) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2611368
- 产品信息
商品描述
靶点-Target
Tyrosine Hydroxylase
反应性
Human,Mouse,Rat,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
60kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Tyrosine Hydroxylase around the phosphorylation site of Ser31. AA range:1-50
特异性
Phospho-TH (S62) Polyclonal Antibody detects endogenous levels of TH protein only when phosphorylated at S62.
基因名称
TH
蛋白名称
Tyrosine 3-monooxygenase (Tyrosine 3-hydroxylase) (TH),Tyrosine Hydrolase
别名
TH;TYH;Tyrosine 3-monooxygenase;Tyrosine 3-hydroxylase;TH
Organism-1
Human
基因ID-1
7054
SwissProt-1
P07101
Organism-2
Mouse
基因ID-2
21823
SwissProt-2
P24529
Organism-3
Rat
基因ID-3
25085
SwissProt-3
P04177
背景
The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, perinuclear region . Nucleus . Cell projection, axon . Cytoplasm . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle . When phosphorylated at Ser-19 shows a nuclear distribution and when phosphorylated at Ser-31 as well at Ser-40 shows a cytosolic distribution (By similarity). Expressed in dopaminergic axons and axon terminals. .
