IRS-1 (phospho Ser312) Polyclonal Antibody一抗

靶点-Target
IRS-1
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
170kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser312. AA range:279-328
特异性
Phospho-IRS-1 (S312) Polyclonal Antibody detects endogenous levels of IRS-1 protein only when phosphorylated at S312.
基因名称
IRS1
蛋白名称
Insulin receptor substrate 1
别名
IRS1;Insulin receptor substrate 1;IRS-1
Organism-1
Human
基因ID-1
3667
SwissProt-1
P35568
Organism-2
Mouse
基因ID-2
16367
SwissProt-2
P35569
Organism-3
Rat
基因ID-3
25467
SwissProt-3
P35570
背景
This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009],
细胞定位
nucleus,cytoplasm,cytosol,plasma membrane,insulin receptor complex,caveola,intracellular membrane-bounded organelle,

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IRS-1 (phospho Ser312) Polyclonal Antibody