KIF2C (phospho Ser95) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611346
- 产品信息
商品描述
靶点-Target
KIF2C
反应性
Human,Mouse
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
80kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human KIF2C around the phosphorylation site of Ser95. AA range:61-110
特异性
Phospho-KIF2C (S95) Polyclonal Antibody detects endogenous levels of KIF2C protein only when phosphorylated at S95.
基因名称
KIF2C
蛋白名称
Kinesin-like protein KIF2C
别名
KIF2C;KNSL6;Kinesin-like protein KIF2C;Kinesin-like protein 6;Mitotic centromere-associated kinesin;MCAK
Organism-1
Human
基因ID-1
11004
SwissProt-1
Q99661
Organism-2
Mouse
基因ID-2
73804
SwissProt-2
Q922S8
背景
kinesin family member 2C(KIF2C) Homo sapiens This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
细胞定位
Cytoplasm, cytoskeleton . Nucleus . Chromosome, centromere . Chromosome, centromere, kinetochore . Associates with the microtubule network at the growing distal tip (the plus-end) of microtubules, probably through interaction with MTUS2/TIP150 and MAPRE1 (By similarity). Association with microtubule plus ends is also mediated by interaction with KIF18B. Centromeric localization requires the presence of BUB1 and SGO2. .





