Na+/K+-ATPase α1 (phospho Ser23) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611343
- 产品信息
商品描述
靶点-Target
Na+/K+-ATPase α1
反应性
Rat
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
113kD
推荐稀释比
WB 1:500-1:2000;IF 1:100-1:300;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from rat ATP1 alpha1/Na+K+ ATPase1 around the phosphorylation site of Ser23. AA range:15-64
特异性
Phospho-Na+/K+-ATPase α1 (S23) Polyclonal Antibody detects endogenous levels of Na+/K+-ATPase α1 protein only when phosphorylated at S23.
基因名称
ATP1A1
蛋白名称
Sodium/potassium-transporting ATPase subunit alpha-1
别名
ATP1A1;Sodium/potassium-transporting ATPase subunit alpha-1;Na;+;/K;+;ATPase alpha-1 subunit;Sodium pump subunit alpha-1
Organism-1
Human
基因ID-1
476
SwissProt-1
P05023
Organism-3
Rat
基因ID-3
24211
SwissProt-3
P06685
背景
The ATPase Na+/K+ transporting subunit alpha 1 encoded by ATP1A1 belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.





