MARCKS (phospho Ser159) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611305
- 产品信息
商品描述
靶点-Target
MARCKS
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
35kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MARCKS around the phosphorylation site of Ser158. AA range:126-175
特异性
Phospho-MARCKS (S158) Polyclonal Antibody detects endogenous levels of MARCKS protein only when phosphorylated at S158.
基因名称
MARCKS
蛋白名称
Myristoylated alanine-rich C-kinase substrate
别名
MARCKS;MACS;PRKCSL;Myristoylated alanine-rich C-kinase substrate;MARCKS;Protein kinase C substrate;80 kDa protein, light chain;80K-L protein;PKCSL
Organism-1
Human
基因ID-1
4082
SwissProt-1
P29966
Organism-2
Mouse
基因ID-2
17118
SwissProt-2
P26645
Organism-3
Rat
SwissProt-3
P30009
背景
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytoskeleton . Membrane ; Lipid-anchor .





