Dab1 (phospho Tyr232) Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611302

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商品描述
  • 靶点-Target

    Dab1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    80kD

  • 推荐稀释比

    WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human Dab1 around the phosphorylation site of Tyr232. AA range:199-248

  • 特异性

    Phospho-Dab1 (Y232) Polyclonal Antibody detects endogenous levels of Dab1 protein only when phosphorylated at Y232.

  • 基因名称

    DAB1

  • 蛋白名称

    Disabled homolog 1

  • 别名

    DAB1;Disabled homolog 1

  • Organism-1

    Human

  • 基因ID-1

    8674

  • SwissProt-1

    O75553

  • Organism-2

    Mouse

  • 基因ID-2

    13131

  • SwissProt-2

    P97318

  • Organism-3

    Rat

  • 基因ID-3

    266729

  • SwissProt-3

    Q8CJH2

  • 背景

    The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008],

  • 细胞定位

    nucleolus,microtubule organizing center,cytosol,brush border,postsynaptic density,membrane,neuron projection,neuronal cell body,intracellular membrane-bounded organelle,apical part of cell,perinuclear region of cytoplasm,