FGF-2 Polyclonal Antibody
¥680.00
Neuro D (phospho Ser274) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2611254
- 产品信息
商品描述
靶点-Target
Neuro D
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
36kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Neuro D around the phosphorylation site of Ser274. AA range:240-289
特异性
Phospho-Neuro D (S274) Polyclonal Antibody detects endogenous levels of Neuro D protein only when phosphorylated at S274.
基因名称
NEUROD1
蛋白名称
Neurogenic differentiation factor 1
别名
NEUROD1;BHLHA3;NEUROD;Neurogenic differentiation factor 1;NeuroD;NeuroD1;Class A basic helix-loop-helix protein 3;bHLHa3
Organism-1
Human
基因ID-1
4760
SwissProt-1
Q13562
Organism-2
Mouse
基因ID-2
18012
SwissProt-2
Q60867
Organism-3
Rat
基因ID-3
29458
SwissProt-3
Q64289
背景
This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . In pancreatic islet cells, shuttles to the nucleus in response to glucose stimulation (By similarity). Colocalizes with NR0B2 in the nucleus. .
