FGF-2 Polyclonal Antibody
¥680.00
Gab 2 (phospho Tyr452) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2611251
- 产品信息
商品描述
靶点-Target
Gab2
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
75kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized phospho-peptide around the phosphorylation site of human Gab 2 (phospho Tyr452)
特异性
Phospho-Gab 2 (Y452) Polyclonal Antibody detects endogenous levels of Gab 2 protein only when phosphorylated at Y452.
基因名称
GAB2
蛋白名称
GRB2-associated-binding protein 2
别名
GAB2;KIAA0571;GRB2-associated-binding protein 2;GRB2-associated binder 2;Growth factor receptor bound protein 2-associated protein 2;pp100
Organism-1
Human
基因ID-1
9846
SwissProt-1
Q9UQC2
Organism-2
Mouse
SwissProt-2
Q9Z1S8
Organism-3
Rat
基因ID-3
84477
SwissProt-3
Q9EQH1
背景
GRB2 associated binding protein 2(GAB2) Homo sapiens This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009],
细胞定位
Cytoplasm . Cell membrane .
