FGF-2 Polyclonal Antibody
¥680.00
Claudin-6 (phospho Tyr219) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2611246
- 产品信息
商品描述
靶点-Target
Claudin-6
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
23kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Claudin 6 around the phosphorylation site of Tyr219. AA range:171-220
特异性
Phospho-Claudin-6 (Y219) Polyclonal Antibody detects endogenous levels of Claudin-6 protein only when phosphorylated at Y219.
基因名称
CLDN6
蛋白名称
Claudin-6
别名
CLDN6;Claudin-6;Skullin
Organism-1
Human
基因ID-1
9074
SwissProt-1
P56747
Organism-2
Mouse
基因ID-2
54419
SwissProt-2
Q9Z262
背景
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010],
细胞定位
Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein .
