Claudin-3 (phospho Tyr219) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611245
- 产品信息
商品描述
靶点-Target
Claudin 3
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
28kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Claudin 3 around the phosphorylation site of Tyr219. AA range:171-220
特异性
Phospho-Claudin-3 (Y219) Polyclonal Antibody detects endogenous levels of Claudin-3 protein only when phosphorylated at Y219.
基因名称
CLDN3
蛋白名称
Claudin-3
别名
CLDN3;C7orf1;CPETR2;Claudin-3;Clostridium perfringens enterotoxin receptor 2;CPE-R 2;CPE-receptor 2;Rat ventral prostate.1 protein homolog;hRVP1
Organism-1
Human
基因ID-1
1365
SwissProt-1
O15551
Organism-2
Mouse
SwissProt-2
Q9Z0G9
背景
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008],
细胞定位
Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein .





