Dynamin I (phospho Ser778) Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611228

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商品描述
  • 靶点-Target

    Dynamin I

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    100kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human DYN1 around the phosphorylation site of Ser778. AA range:751-800

  • 特异性

    Phospho-Dynamin I (S778) Polyclonal Antibody detects endogenous levels of Dynamin I protein only when phosphorylated at S778.

  • 基因名称

    DNM1

  • 蛋白名称

    Dynamin-1

  • 别名

    DNM1;DNM;Dynamin-1

  • Organism-1

    Human

  • 基因ID-1

    1759

  • SwissProt-1

    Q05193

  • Organism-2

    Mouse

  • 基因ID-2

    13429

  • SwissProt-2

    P39053

  • Organism-3

    Rat

  • 基因ID-3

    140694

  • SwissProt-3

    P21575

  • 背景

    dynamin 1(DNM1) Homo sapiens This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cytoplasm . Cytoplasm, cytoskeleton . Microtubule-associated.