Mnk1 (phospho Thr255) Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611208

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商品描述
  • 靶点-Target

    Mnk1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    60kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human MNK1 around the phosphorylation site of Thr255. AA range:221-270

  • 特异性

    Phospho-Mnk1 (T255) Polyclonal Antibody detects endogenous levels of Mnk1 protein only when phosphorylated at T255.

  • 基因名称

    MKNK1

  • 蛋白名称

    MAP kinase-interacting serine/threonine-protein kinase 1

  • 别名

    MKNK1;MNK1;MAP kinase-interacting serine/threonine-protein kinase 1;MAP kinase signal-integrating kinase 1;MAPK signal-integrating kinase 1;Mnk1

  • Organism-1

    Human

  • 基因ID-1

    8569

  • SwissProt-1

    Q9BUB5

  • Organism-2

    Mouse

  • 基因ID-2

    17346

  • SwissProt-2

    O08605

  • Organism-3

    Rat

  • 基因ID-3

    500526

  • SwissProt-3

    Q4G050

  • 背景

    MAP kinase interacting serine/threonine kinase 1(MKNK1) Homo sapiens This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012],

  • 细胞定位

    [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm. Nucleus.