FGF-2 Polyclonal Antibody
¥680.00
MEK-7 (phospho Thr275) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
一键复制产品信息
产品规格：
- 50μL
- 100μL
货号：
FAB2611207
- 产品信息
商品描述
靶点-Target
MKK7
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
43kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MAP2K7 around the phosphorylation site of Thr275. AA range:241-290
特异性
Phospho-MEK-7 (T275) Polyclonal Antibody detects endogenous levels of MEK-7 protein only when phosphorylated at T275.
基因名称
MAP2K7
蛋白名称
Dual specificity mitogen-activated protein kinase kinase 7
别名
MAP2K7;JNKK2;MEK7;MKK7;PRKMK7;SKK4;Dual specificity mitogen-activated protein kinase kinase 7;MAP kinase kinase 7;MAPKK 7;JNK-activating kinase 2;MAPK/ERK kinase 7;MEK 7;Stress-activated protein kinase kinase 4;SAPK kinase 4;S
Organism-1
Human
基因ID-1
5609
SwissProt-1
O14733
Organism-2
Mouse
基因ID-2
26400
SwissProt-2
Q8CE90
Organism-3
Rat
基因ID-3
363855
SwissProt-3
Q4KSH7
背景
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
细胞定位
Nucleus. Cytoplasm .
