Cdc25A (phospho Thr507) Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611185

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商品描述
  • 靶点-Target

    Cdc25A

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    59kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized phospho-peptide around the phosphorylation site of human Cdc25A (phospho Thr507)

  • 特异性

    Phospho-Cdc25A (T507) Polyclonal Antibody detects endogenous levels of Cdc25A protein only when phosphorylated at T507.

  • 基因名称

    CDC25A

  • 蛋白名称

    M-phase inducer phosphatase 1

  • 别名

    CDC25A;M-phase inducer phosphatase 1;Dual specificity phosphatase Cdc25A

  • Organism-1

    Human

  • 基因ID-1

    993

  • SwissProt-1

    P30304

  • Organism-2

    Mouse

  • SwissProt-2

    P48964

  • Organism-3

    Rat

  • 基因ID-3

    171102

  • SwissProt-3

    P48965

  • 背景

    cell division cycle 25A(CDC25A) Homo sapiens CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

  • 细胞定位

    intracellular,nucleus,nucleoplasm,cytoplasm,cytosol,