Casein Kinase IIα (phospho Tyr255) Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611172

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商品描述
  • 靶点-Target

    Casein Kinase IIα

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    45kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human Casein Kinase II alpha around the phosphorylation site of Tyr255. AA range:221-270

  • 特异性

    Phospho-Casein Kinase IIα (Y255) Polyclonal Antibody detects endogenous levels of Casein Kinase IIα protein only when phosphorylated at Y255.

  • 基因名称

    CSNK2A1

  • 蛋白名称

    Casein kinase II subunit alpha

  • 别名

    CSNK2A1;CK2A1;Casein kinase II subunit alpha;CK II alpha

  • Organism-1

    Human

  • 基因ID-1

    1457

  • SwissProt-1

    P68400

  • Organism-2

    Mouse

  • 基因ID-2

    12995

  • SwissProt-2

    Q60737

  • Organism-3

    Rat

  • 基因ID-3

    116549

  • SwissProt-3

    P19139

  • 背景

    Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene. [provided by RefSeq, Jul 2014],

  • 细胞定位

    Nucleus .