C3G (phospho Tyr504) Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2611158
- 产品信息
商品描述
靶点-Target
C3G
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
120kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RapGEF1 around the phosphorylation site of Tyr504. AA range:470-519
特异性
Phospho-C3G (Y504) Polyclonal Antibody detects endogenous levels of C3G protein only when phosphorylated at Y504.
基因名称
RAPGEF1
蛋白名称
Rap guanine nucleotide exchange factor 1
别名
RAPGEF1;GRF2;Rap guanine nucleotide exchange factor 1;CRK SH3-binding GNRP;Guanine nucleotide-releasing factor 2;Protein C3G
Organism-1
Human
基因ID-1
2889
SwissProt-1
Q13905
背景
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008],
细胞定位
Early endosome .





