Ron (phospho Ser1394) Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611127

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商品描述
  • 靶点-Target

    Ron

  • 反应性

    Human,Mouse

  • 应用

    WB,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    152kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human CD136/RON around the phosphorylation site of Ser1394. AA range:1351-1400

  • 特异性

    Phospho-Ron (S1394) Polyclonal Antibody detects endogenous levels of Ron protein only when phosphorylated at S1394.

  • 基因名称

    MST1R

  • 蛋白名称

    Macrophage-stimulating protein receptor

  • 别名

    MST1R;PTK8;RON;Macrophage-stimulating protein receptor;MSP receptor;CDw136;Protein-tyrosine kinase 8;p185-Ron;CD antigen CD136

  • Organism-1

    Human

  • 基因ID-1

    4486

  • SwissProt-1

    Q04912

  • Organism-2

    Mouse

  • 基因ID-2

    19882

  • SwissProt-2

    Q62190

  • 背景

    This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016],

  • 细胞定位

    Membrane; Single-pass type I membrane protein.