FGF-2 Polyclonal Antibody
¥680.00
p38 (phospho Thr180/Y182) Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2611119
- 产品信息
商品描述
靶点-Target
p38
反应性
Human,Mouse,Rat,GuineaPig
应用
IF,WB,Flow Cyt,IHC,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
38kD
推荐稀释比
IF/ICC1:100-500;WB 1:500-2000;Flow Cyt 1:50-200;IHC 1:100-500;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human p38 MAPK around the phosphorylation site of Thr179 and Tyr181. AA range:151-200
特异性
Phospho-p38 (T180/Y182) Polyclonal Antibody detects endogenous levels of p38 protein only when phosphorylated at T180/Y182.
基因名称
MAPK14
蛋白名称
Mitogen-activated protein kinase 14
别名
MAPK14;CSBP;CSBP1;CSBP2;CSPB1;MXI2;SAPK2A;Mitogen-activated protein kinase 14;MAP kinase 14;MAPK 14;Cytokine suppressive anti-inflammatory drug-binding protein;CSAID-binding protein;CSBP;MAP kinase MXI2;MAX-interacting protein
Organism-1
Human
基因ID-1
1432
SwissProt-1
Q16539
Organism-2
Mouse
基因ID-2
26416
SwissProt-2
P47811
Organism-3
Rat
SwissProt-3
P70618
背景
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding d
细胞定位
Cytoplasm . Nucleus .
