ATRIP (phospho Ser68) Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2611117

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商品描述
  • 靶点-Target

    ATRIP

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Observed)

    80kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human ATRIP around the phosphorylation site of Ser68. AA range:34-83

  • 特异性

    Phospho-ATRIP (S68) Polyclonal Antibody detects endogenous levels of ATRIP protein only when phosphorylated at S68.

  • 基因名称

    ATRIP

  • 蛋白名称

    ATR-interacting protein

  • 别名

    ATRIP;AGS1;ATR-interacting protein;ATM and Rad3-related-interacting protein

  • Organism-1

    Human

  • 基因ID-1

    84126

  • SwissProt-1

    Q8WXE1

  • Organism-2

    Mouse

  • 基因ID-2

    235610

  • SwissProt-2

    Q8BMG1

  • 背景

    This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012],

  • 细胞定位

    Nucleus . Redistributes to discrete nuclear foci upon DNA damage.